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  6. Isogentisin

Isogentisin is a cell protector. Isogentisin can shield human umbilical vein endothelial cells (HUVEC) from cell death caused by H202 and UV exposure. Isogentisin can also prevent endothelial damage triggered by smoking by activating cell repair functions to promote cell survival.

For research use only. We do not sell to patients.

Isogentisin Chemical Structure

Isogentisin Chemical Structure

CAS No. : 491-64-5

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Description

Isogentisin is a cell protector. Isogentisin can shield human umbilical vein endothelial cells (HUVEC) from cell death caused by H202 and UV exposure. Isogentisin can also prevent endothelial damage triggered by smoking by activating cell repair functions to promote cell survival[1].
Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
93.21 μM
Compound: 2b
Growth inhibition of human HepG2 cells after 24 hrs by MTT assay
Growth inhibition of human HepG2 cells after 24 hrs by MTT assay
[PMID: 29609121]
MCF7 IC50
> 200 μM
Compound: 2b
Growth inhibition of human MCF7 cells after 24 hrs by MTT assay
Growth inhibition of human MCF7 cells after 24 hrs by MTT assay
[PMID: 29609121]
MDA-MB-231 IC50
> 200 μM
Compound: 2b
Growth inhibition of human MDA-MB-231 cells after 24 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 24 hrs by MTT assay
[PMID: 29609121]
Molecular Weight

258.23

Formula

C14H10O5
CAS No.
Appearance

Solid

SMILES

O=C1C2=C(C=C(C=C2O)O)OC3=C1C=C(C=C3)OC
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
References
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Isogentisin Related Classifications

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Keywords:

Isogentisin491-64-5OthersCell protectantHUVECendothelial damagecell repairInhibitorinhibitorinhibit

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