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  4. JAG-1, scrambled TFA

JAG-1, scrambled TFA  (Synonyms: scJag-1 TFA)

Cat. No.: HY-P1849A Purity: 99.52%
COA Handling Instructions

JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

JAG-1, scrambled TFA Chemical Structure

JAG-1, scrambled TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 220 In-stock
10 mg USD 330 In-stock
50 mg USD 900 In-stock
100 mg USD 1300 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of JAG-1, scrambled TFA:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control[1].

In Vitro

In contrast to JAG-1, pretreatment of human pulmonary arterial smooth muscle cells (PASMC) with 50 μM scJag-1 TFA for 30 min has no effect on the transient and plateau components of store-operated Ca2+ entry (SOCE) in comparison to the cells treated with vehicle used to dissolve scJag-1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2221.37

Formula

C95H128F3N25O28S3

Appearance

Solid

Color

White to off-white

Sequence Shortening

RCGPDCFDNYGRYKYCF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (45.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (4.50 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4502 mL 2.2509 mL 4.5017 mL
5 mM 0.0900 mL 0.4502 mL 0.9003 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.52%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.4502 mL 2.2509 mL 4.5017 mL 11.2543 mL
DMSO 5 mM 0.0900 mL 0.4502 mL 0.9003 mL 2.2509 mL
10 mM 0.0450 mL 0.2251 mL 0.4502 mL 1.1254 mL
15 mM 0.0300 mL 0.1501 mL 0.3001 mL 0.7503 mL
20 mM 0.0225 mL 0.1125 mL 0.2251 mL 0.5627 mL
25 mM 0.0180 mL 0.0900 mL 0.1801 mL 0.4502 mL
30 mM 0.0150 mL 0.0750 mL 0.1501 mL 0.3751 mL
40 mM 0.0113 mL 0.0563 mL 0.1125 mL 0.2814 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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JAG-1, scrambled TFA
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