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  4. JMV 236

JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intake through the interaction of the intestinal endogenous peptide PrRP and the CCK1 receptor. The administration of JMV 236 activates PrRP neurons located in the NTS, thereby enhancing its appetite-suppressing effect. JMV 236 has significant effects on areas of the central nervous system associated with food intake, especially during states of starvation.

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JMV 236 Chemical Structure

JMV 236 Chemical Structure

CAS No. : 113137-57-8

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JMV 236 Related Antibodies

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Description

JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intake through the interaction of the intestinal endogenous peptide PrRP and the CCK1 receptor. The administration of JMV 236 activates PrRP neurons located in the NTS, thereby enhancing its appetite-suppressing effect. JMV 236 has significant effects on areas of the central nervous system associated with food intake, especially during states of starvation[1].

Molecular Weight

1207.31

Formula

C56H74N10O18S
CAS No.
Sequence

{Boc-Tyr(SO3)}-Nle-Gly-Trp-Nle-Asp-Phe-NH2
Sequence Shortening

{Boc-Tyr(SO3)}-{Nle}-GW-{Nle}-DF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JMV 236 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JMV 236113137-57-8JMV236JMV-236OthersInhibitorinhibitorinhibit

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