2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Sodium Channel Calcium Channel
  4. JNJ-26990990

JNJ-26990990 is a broad-spectrum antiepileptic agent with oral activity. JNJ-26990990 can inhibit voltage-gated Na+ channels and N-type Ca2+ channels, but has a very weak inhibitory effect on human carbonic anhydrase-II (IC50 = 110 μM).

For research use only. We do not sell to patients.

JNJ-26990990 Chemical Structure

JNJ-26990990 Chemical Structure

CAS No. : 877316-38-6

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Based on 1 publication(s) in Google Scholar

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Description

JNJ-26990990 is a broad-spectrum antiepileptic agent with oral activity. JNJ-26990990 can inhibit voltage-gated Na+ channels and N-type Ca2+ channels, but has a very weak inhibitory effect on human carbonic anhydrase-II (IC50 = 110 μM)[1].

Molecular Weight

242.32

Formula

C9H10N2O2S2
CAS No.
SMILES

O=S(N)(NCC1=CSC2=CC=CC=C21)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JNJ-26990990 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-26990990877316-38-6JNJ26990990JNJ 26990990Sodium ChannelCalcium ChannelNa channelsNa+ channelsCa2+ channelsCa channelsepilepsyInhibitorinhibitorinhibit

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