2. Metabolic Enzyme/Protease
  3. Aminopeptidase
  4. JNJ-26993135

JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM.

For research use only. We do not sell to patients.

JNJ-26993135 Chemical Structure

JNJ-26993135 Chemical Structure

CAS No. : 841202-16-2

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Based on 1 publication(s) in Google Scholar

JNJ-26993135 Related Antibodies

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CD13 Leukotriene A4 hydrolase

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Description

JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM[1].

Molecular Weight

368.45

Formula

C20H20N2O3S
CAS No.
SMILES

O=C(C1CCN(CC2=CC=C(OC3=NC4=CC=CC=C4S3)C=C2)CC1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (33.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7141 mL 13.5704 mL 27.1407 mL
5 mM 0.5428 mL 2.7141 mL 5.4281 mL
View the Complete Stock Solution Preparation Table

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7141 mL 13.5704 mL 27.1407 mL 67.8518 mL
5 mM 0.5428 mL 2.7141 mL 5.4281 mL 13.5704 mL
10 mM 0.2714 mL 1.3570 mL 2.7141 mL 6.7852 mL
15 mM 0.1809 mL 0.9047 mL 1.8094 mL 4.5235 mL
20 mM 0.1357 mL 0.6785 mL 1.3570 mL 3.3926 mL
25 mM 0.1086 mL 0.5428 mL 1.0856 mL 2.7141 mL
30 mM 0.0905 mL 0.4523 mL 0.9047 mL 2.2617 mL
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JNJ-26993135 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-26993135841202-16-2JNJ26993135JNJ 26993135Aminopeptidaseasthmaallergic rhinitisInhibitorinhibitorinhibit

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