2. Anti-infection Cell Cycle/DNA Damage
  3. HIV CDK
  4. JTK-101

JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research.

For research use only. We do not sell to patients.

JTK-101 Chemical Structure

JTK-101 Chemical Structure

CAS No. : 503048-34-8

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JTK-101 Related Antibodies

Top Publications Citing Use of Products

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HIV HIV-1 HIV-2

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

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Description

JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research[1].

IC50 & Target

HIV-1

 

CDK9/cyclinT1

 

Molecular Weight

413.47

Formula

C25H23N3O3
CAS No.
SMILES

N#CC1=CC=C(C=C1)CN2CCC(CC2)(OC3=C4C=C(C=CC4=CC=C35)OC)NC5=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JTK-101 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JTK-101503048-34-8JTK101JTK 101HIVCDKHuman immunodeficiency virusCyclin dependent kinaseInhibitorinhibitorinhibit

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