1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. K1833

K1833 is a hrAChE inhibitor/reactivator, with an IC50 of 58 μM. K1833 also shows high inhibition (IC50=0.57μM) and low reactivation for hrBChE.

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K1833 Chemical Structure

K1833 Chemical Structure

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Description

K1833 is a hrAChE inhibitor/reactivator, with an IC50 of 58 μM. K1833 also shows high inhibition (IC50=0.57μM) and low reactivation for hrBChE[1].

IC50 & Target[1]

hAChE

58 μM (IC50)

hBCHE

0.57 μM (IC50)

Molecular Weight

679.16

Formula

C26H28BBr2F2N7O2

SMILES

FB1(F)N2C=CC=C2C(NCCNC(C3=CC=[N+](CCC[N+]4=CC=C(/C=N/O)C=C4)C=C3)=O)=C5C=CC=[N]15.[Br-].[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
K1833
Cat. No.:
HY-155284
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