K203

Cat. No.: HY-146959: FAQs
Data Sheet Handling Instructions

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K203 is a potent reactivator of tabun-inhibited AChE. K203 is a crucial antidote used for the organophosphate intoxication.

For research use only. We do not sell to patients.

K203 Chemical Structure

CAS No. : 955034-69-2

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Description

K203 is a potent reactivator of tabun-inhibited AChE. K203 is a crucial antidote used for the organophosphate intoxication^[1].

IC₅₀ & Target

AChE

Molecular Weight

458.15

Formula

C₁₆H₁₈Br₂N₄O₂

CAS No.

955034-69-2

SMILES

NC(C1=CC=[N+](C=C1)C/C=C/C[N+]2=CC=C(C=C2)/C=N/O)=O.[Br-].[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kamil Musilek, et al. Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203). J Med Chem. 2007 Nov 1;50(22):5514-8. [Content Brief]

K203 Related Classifications

Neurological Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

K203955034-69-2K 203K-203Cholinesterase (ChE)Inhibitorinhibitorinhibit

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