2. Protein Tyrosine Kinase/RTK
  3. RET c-Kit PDGFR
  4. KBP-7018

KBP-7018 is a tyrosine kinase-selective inhibitor. KBP-7018 has potent inhibitory effects on c-KIT, PDGFR, and RET with IC50 values of 10 nM, 7.6 nM and 25 nM, respectively. KBP-7018 can be used for the research of idiopathic pulmonary fibrosis.

For research use only. We do not sell to patients.

KBP-7018 Chemical Structure

KBP-7018 Chemical Structure

CAS No. : 1613437-66-3

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Other Forms of KBP-7018:

KBP-7018 Related Antibodies

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Description

KBP-7018 is a tyrosine kinase-selective inhibitor. KBP-7018 has potent inhibitory effects on c-KIT, PDGFR, and RET with IC50 values of 10 nM, 7.6 nM and 25 nM, respectively. KBP-7018 can be used for the research of idiopathic pulmonary fibrosis[1].
IC50 & Target

IC50: c-KIT (10 nM), PDGFR (7.6 nM), and RET (25 nM)[1].
Molecular Weight

538.59

Formula

C31H30N4O5
CAS No.
SMILES

O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC4=C(N(C(CN5CCOCC5)=O)CC4)C=C3)/C6=CC=CC=C6)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KBP-7018 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KBP-70181613437-66-3KBP7018KBP 7018RETc-KitPDGFRSCFRCD117Platelet-derived growth factor receptortyrosine kinase-selectivec-KITidiopathic pulmonary fibrosisInhibitorinhibitorinhibit

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HY-117873
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