L-Asparagine-amide-¹⁵N monohydrate

Name: L-Asparagine-amide- 15 N monohydrate
Brand: MedChemExpress
SKU: HY-W017443S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-W017443S1 Purity: 99.80%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Asparagine-amide-¹⁵N (monohydrate) is the ¹⁵N-labeled L-Asparagine (monohydrate). L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

For research use only. We do not sell to patients.

L-Asparagine-amide-<sup>15</sup>N monohydrate Chemical Structure

L-Asparagine-amide-¹⁵N monohydrate Chemical Structure

CAS No. : 204451-47-8

Size	Price	Stock	Quantity
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 640	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Asparagine-amide-¹⁵N monohydrate:

L-Asparagine monohydrate Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

151.13

Formula

C₄H₁₀N¹⁵NO₄

CAS No.

204451-47-8

Appearance

Solid

Color

White to off-white

SMILES

[15NH2]C(C[C@H](N)C(O)=O)=O.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (330.84 mM; Need ultrasonic)

H₂O : 20 mg/mL (132.34 mM; Need ultrasonic)

DMSO : 1 mg/mL (6.62 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6168 mL	33.0841 mL	66.1682 mL
5 mM	1.3234 mL	6.6168 mL	13.2336 mL
10 mM	0.6617 mL	3.3084 mL	6.6168 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.80%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (248 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMSO / H₂O / H₂O	1 mM	6.6168 mL	33.0841 mL	66.1682 mL	165.4205 mL
DMSO / DMSO / H₂O / H₂O	5 mM	1.3234 mL	6.6168 mL	13.2336 mL	33.0841 mL
H₂O / H₂O	10 mM	0.6617 mL	3.3084 mL	6.6168 mL	16.5420 mL
	15 mM	0.4411 mL	2.2056 mL	4.4112 mL	11.0280 mL
	20 mM	0.3308 mL	1.6542 mL	3.3084 mL	8.2710 mL
	25 mM	0.2647 mL	1.3234 mL	2.6467 mL	6.6168 mL
	30 mM	0.2206 mL	1.1028 mL	2.2056 mL	5.5140 mL
	40 mM	0.1654 mL	0.8271 mL	1.6542 mL	4.1355 mL
	50 mM	0.1323 mL	0.6617 mL	1.3234 mL	3.3084 mL
	60 mM	0.1103 mL	0.5514 mL	1.1028 mL	2.7570 mL
	80 mM	0.0827 mL	0.4136 mL	0.8271 mL	2.0678 mL
	100 mM	0.0662 mL	0.3308 mL	0.6617 mL	1.6542 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.