L-Glutathione reduced-¹³C₂,¹⁵N (Synonyms: GSH-¹³C₂,¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine-¹³C₂,¹⁵N)

Cat. No.: HY-D0187S Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Glutathione reduced-¹³C₂,¹⁵N is the ¹³C- and ¹⁵N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

For research use only. We do not sell to patients.

L-Glutathione reduced-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N Chemical Structure

L-Glutathione reduced-¹³C₂,¹⁵N Chemical Structure

CAS No. : 815610-65-2

Size	Price	Stock
1 mg	USD 650	Ask For Quote & Lead Time
5 mg	USD 2080	Ask For Quote & Lead Time

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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

310.30

Formula

C₈¹³C₂H₁₇N₂¹⁵NO₆S

CAS No.

815610-65-2

Unlabeled CAS

70-18-8

Appearance

Solid

Color

White to off-white

SMILES

SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C([15NH][13CH2][13C](O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 62.5 mg/mL (201.42 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2227 mL	16.1134 mL	32.2269 mL
5 mM	0.6445 mL	3.2227 mL	6.4454 mL
10 mM	0.3223 mL	1.6113 mL	3.2227 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (248 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	3.2227 mL	16.1134 mL	32.2269 mL	80.5672 mL
	5 mM	0.6445 mL	3.2227 mL	6.4454 mL	16.1134 mL
	10 mM	0.3223 mL	1.6113 mL	3.2227 mL	8.0567 mL
	15 mM	0.2148 mL	1.0742 mL	2.1485 mL	5.3711 mL
	20 mM	0.1611 mL	0.8057 mL	1.6113 mL	4.0284 mL
	25 mM	0.1289 mL	0.6445 mL	1.2891 mL	3.2227 mL
	30 mM	0.1074 mL	0.5371 mL	1.0742 mL	2.6856 mL
	40 mM	0.0806 mL	0.4028 mL	0.8057 mL	2.0142 mL
	50 mM	0.0645 mL	0.3223 mL	0.6445 mL	1.6113 mL
	60 mM	0.0537 mL	0.2686 mL	0.5371 mL	1.3428 mL
	80 mM	0.0403 mL	0.2014 mL	0.4028 mL	1.0071 mL
	100 mM	0.0322 mL	0.1611 mL	0.3223 mL	0.8057 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

L-Glutathione reduced-¹³C₂,¹⁵N Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Glutathione reduced-¹³C₂,¹⁵N815610-65-2GSH-¹³C₂,¹⁵Nγ-L-Glutamyl-L-cysteinyl-glycine-¹³C₂,¹⁵NEndogenous MetaboliteReactive Oxygen SpeciesFerroptosisInhibitorinhibitorinhibit

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L-Glutathione reduced-13C2,15N (Synonyms: GSH-13C2,15N; γ-L-Glutamyl-L-cysteinyl-glycine-13C2,15N)

Other Forms of L-Glutathione reduced-13C2,15N:

L-Glutathione reduced-13C2,15N Related Antibodies

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References

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Complete Stock Solution Preparation Table

L-Glutathione reduced-13C2,15N Related Classifications