L-Glutathione reduced-¹⁵N (Synonyms: GSH-¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine-¹⁵N)

Cat. No.: HY-D0187S6: FAQs
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L-Glutathione reduced-¹⁵N (GSH-¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine-¹⁵N) is ¹⁵N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.

For research use only. We do not sell to patients.

L-Glutathione reduced-<sup>15</sup>N Chemical Structure

L-Glutathione reduced-¹⁵N Chemical Structure

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1 mg		Get quote	Estimated Time of Arrival: May 15

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Other Forms of L-Glutathione reduced-¹⁵N:

L-Glutathione reduced In-stock
L-Glutathione reduced-¹³C₂,¹⁵N Get quote

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Description	L-Glutathione reduced-¹⁵N (GSH-¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine-¹⁵N) is ¹⁵N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	308.32
Formula	C₁₀H₁₇N₂¹⁵NO₆S
Unlabeled CAS	70-18-8
SMILES	OC(CNC([C@H](CS)[15NH]C(CC[C@H](N)C(O)=O)=O)=O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Help & FAQs

Why are the cells in poor condition after PolyFast transfection?
PolyFast has certain cytotoxicity, and it is normal for cell viability to decrease after transfection. Cells with a density of 70-90%, exponential phase, and a survival rate greater than 90% can be used for transfection.
Can PolyFast be used to transduce RNA?
Yes, RNA transfection can be performed by referring to the DNA transfection method.
Can I use complete medium for transfection?
No, serum and antibiotics will affect the stability of the transfection complex. It is recommended to use a basal culture medium that does not contain serum or antibiotics.
Do I need to change the culture medium after transfection?
If necessary, the culture medium containing serum and antibiotics can be replaced 6 hours after transfection.
Can PolyFast be used to transfect suspension cells?
Generally, it is recommended that you use a transfection reagent specifically for suspension cells. We have not verified the transfection effect of suspension cells yet. If you want to use this kit to transfect suspension cells, you can try to reduce the shaking speed after transfection to promote full contact between the PolyFast-DNA complex and the cells, increase the uptake rate, and avoid cell sedimentation, aggregation or hypoxia. After transfection for 6 hours, you can increase the shaking speed to the normal speed.

Keywords:

L-Glutathione reduced-¹⁵NGSH-¹⁵N γ-L-Glutamyl-L-cysteinyl-glycine-¹⁵NIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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L-Glutathione reduced-15N (Synonyms: GSH-15N; γ-L-Glutamyl-L-cysteinyl-glycine-15N)

Other Forms of L-Glutathione reduced-15N:

Biological Activity

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L-Glutathione reduced-15N Related Classifications

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