L-Glyceric acid sodium

Name: L-Glyceric acid sodium
Brand: MedChemExpress
SKU: HY-113377A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113377A Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2.

For research use only. We do not sell to patients.

L-Glyceric acid sodium Chemical Structure

CAS No. : 146298-95-5

Size	Price	Stock	Quantity
5 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Glyceric acid sodium:

L-Glyceric acid Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

Human Endogenous Metabolite

In Vitro

Primary hyperoxaluria type 2 (PH2), also called L-glyceric aciduria. The metabolic defect is due to deficiencies of D-glycerate dehydrogenase and glyoxylate reductase, leading to excretion of L-Glyceric acid, and L-Glyceric acid is the cornerstone for the diagnosis of PH2^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

128.06

Formula

C₃H₅NaO₄

CAS No.

146298-95-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])[C@@H](O)CO

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (390.44 mM; Need ultrasonic)

DMSO : 10 mg/mL (78.09 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.8088 mL	39.0442 mL	78.0884 mL
5 mM	1.5618 mL	7.8088 mL	15.6177 mL
10 mM	0.7809 mL	3.9044 mL	7.8088 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (247 KB) Elemental Analysis Report (105 KB)

Handling Instructions (2659 KB)

References

[1]. Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16(3):191-8. [Content Brief]

[2]. Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18(10):986-91. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	7.8088 mL	39.0442 mL	78.0884 mL	195.2210 mL
	5 mM	1.5618 mL	7.8088 mL	15.6177 mL	39.0442 mL
	10 mM	0.7809 mL	3.9044 mL	7.8088 mL	19.5221 mL
	15 mM	0.5206 mL	2.6029 mL	5.2059 mL	13.0147 mL
	20 mM	0.3904 mL	1.9522 mL	3.9044 mL	9.7610 mL
	25 mM	0.3124 mL	1.5618 mL	3.1235 mL	7.8088 mL
	30 mM	0.2603 mL	1.3015 mL	2.6029 mL	6.5074 mL
	40 mM	0.1952 mL	0.9761 mL	1.9522 mL	4.8805 mL
	50 mM	0.1562 mL	0.7809 mL	1.5618 mL	3.9044 mL
	60 mM	0.1301 mL	0.6507 mL	1.3015 mL	3.2537 mL
H₂O	80 mM	0.0976 mL	0.4881 mL	0.9761 mL	2.4403 mL
H₂O	100 mM	0.0781 mL	0.3904 mL	0.7809 mL	1.9522 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.