L-Lysine-d₉ hydrochloride

Name: L-Lysine-d 9 hydrochloride
Brand: MedChemExpress
SKU: HY-N0470S5
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0470S5 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Lysine-d₉ (hydrochloride) is the deuterium labeled L-Lysine. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.

For research use only. We do not sell to patients.

L-Lysine-d<sub>9</sub> hydrochloride Chemical Structure

L-Lysine-d₉ hydrochloride Chemical Structure

CAS No. : 2708343-64-8

Size	Price	Stock	Quantity
1 mg	USD 98	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 333	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 535	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Lysine-d₉ hydrochloride:

L-Lysine hydrochloride In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

191.70

Formula

C₆H₆D₉ClN₂O₂

CAS No.

2708343-64-8

Unlabeled CAS

657-27-2

Appearance

Solid

Color

White to off-white

SMILES

N[C@@](C(O)=O)([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])N.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (521.65 mM; Need ultrasonic)

DMSO : ≥ 1 mg/mL (5.22 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.2165 mL	26.0824 mL	52.1648 mL
5 mM	1.0433 mL	5.2165 mL	10.4330 mL
10 mM	0.5216 mL	2.6082 mL	5.2165 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [Content Brief]

[3]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009. [Content Brief]

[4]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O / H₂O	1 mM	5.2165 mL	26.0824 mL	52.1648 mL	130.4121 mL
DMSO / H₂O / H₂O	5 mM	1.0433 mL	5.2165 mL	10.4330 mL	26.0824 mL
H₂O / H₂O	10 mM	0.5216 mL	2.6082 mL	5.2165 mL	13.0412 mL
	15 mM	0.3478 mL	1.7388 mL	3.4777 mL	8.6941 mL
	20 mM	0.2608 mL	1.3041 mL	2.6082 mL	6.5206 mL
	25 mM	0.2087 mL	1.0433 mL	2.0866 mL	5.2165 mL
	30 mM	0.1739 mL	0.8694 mL	1.7388 mL	4.3471 mL
	40 mM	0.1304 mL	0.6521 mL	1.3041 mL	3.2603 mL
	50 mM	0.1043 mL	0.5216 mL	1.0433 mL	2.6082 mL
	60 mM	0.0869 mL	0.4347 mL	0.8694 mL	2.1735 mL
	80 mM	0.0652 mL	0.3260 mL	0.6521 mL	1.6302 mL
	100 mM	0.0522 mL	0.2608 mL	0.5216 mL	1.3041 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.