1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Lysine hydrate

L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis.

For research use only. We do not sell to patients.

L-Lysine hydrate Chemical Structure

L-Lysine hydrate Chemical Structure

CAS No. : 39665-12-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
USD 22 In-stock
Solution
10 mM * 1 mL in Water USD 22 In-stock
Solid
1 g USD 20 In-stock
5 g USD 30 In-stock
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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of L-Lysine hydrate:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2].

IC50 & Target[1][2]

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

L-Lysine hydrate (VSMCs) suppresses plasma iPTH and elevates plasma alanine, proline, plasma arginine, and homo arginine, thereby inhibiting apoptosis of VSMCs and mineral precipitation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

L-Lysine hydrate (40 μg/kg; p.o.) ameliorates arterial calcification in adenine rats and protects the femora from osteoporotic changes in adenine rats[1].
L-Lysine hydrate (10 and 400 mg/kg; i.g. and p.o.; Male mice) inhibits pancreatic tissue damage[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male mice[2]
Dosage: 10 and 400 mg/kg
Administration: Intraperitoneal injection and oral administration; for 15 days
Result: Inhibited the release of the inflammatory cytokine IL-6 and enhance antioxidant activity.
Molecular Weight

164.20

Formula

C6H16N2O3

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

N[C@H](C(O)=O)CCCCN.O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (609.01 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0901 mL 30.4507 mL 60.9013 mL
5 mM 1.2180 mL 6.0901 mL 12.1803 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.95%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.0901 mL 30.4507 mL 60.9013 mL 152.2534 mL
5 mM 1.2180 mL 6.0901 mL 12.1803 mL 30.4507 mL
10 mM 0.6090 mL 3.0451 mL 6.0901 mL 15.2253 mL
15 mM 0.4060 mL 2.0300 mL 4.0601 mL 10.1502 mL
20 mM 0.3045 mL 1.5225 mL 3.0451 mL 7.6127 mL
25 mM 0.2436 mL 1.2180 mL 2.4361 mL 6.0901 mL
30 mM 0.2030 mL 1.0150 mL 2.0300 mL 5.0751 mL
40 mM 0.1523 mL 0.7613 mL 1.5225 mL 3.8063 mL
50 mM 0.1218 mL 0.6090 mL 1.2180 mL 3.0451 mL
60 mM 0.1015 mL 0.5075 mL 1.0150 mL 2.5376 mL
80 mM 0.0761 mL 0.3806 mL 0.7613 mL 1.9032 mL
100 mM 0.0609 mL 0.3045 mL 0.6090 mL 1.5225 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Lysine hydrate
Cat. No.:
HY-W015370
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