2. Immunology/Inflammation
  3. NO Synthase
  4. L-NMMA

L-NMMA  (Synonyms: Tilarginine; Methylarginine)

Cat. No.: HY-18732
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L-NMMA (Tilarginine; Methylarginine) competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO). L-NMMA is utilized as NO synthase antagonist in experimental settings.

For research use only. We do not sell to patients.

L-NMMA Chemical Structure

L-NMMA Chemical Structure

CAS No. : 17035-90-4

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L-NMMA Related Antibodies

Top Publications Citing Use of Products

    L-NMMA purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2023 Jan;24(1):162-173.  [Abstract]

    L-NMMA acetate (200 μM; 48 h) leads to elevating ammonia and inhibiting CD8+ TM cell induction, in parallel with the inhibition of NO production.

    View All NO Synthase Isoform Specific Products:

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    nNOS iNOS eNOS

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    Description

    L-NMMA (Tilarginine; Methylarginine) competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO). L-NMMA is utilized as NO synthase antagonist in experimental settings[1].

    Molecular Weight

    188.23

    Formula

    C7H16N4O2
    CAS No.
    SMILES

    OC([C@@H](N)CCCNC(NC)=N)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    L-NMMA Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-NMMA17035-90-4Tilarginine MethylarginineNO SynthaseNitric oxide synthasesNOScompetitiveInhibitorinhibitorinhibit

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