L202

Cat. No.: HY-158796: FAQs
Data Sheet Handling Instructions

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L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles.

For research use only. We do not sell to patients.

L202 Chemical Structure

CAS No. : 2170488-92-1

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Description	L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles^[1].
Molecular Weight	650.07
Formula	C₄₁H₇₉NO₄
CAS No.	2170488-92-1
SMILES	O=C(CCCCCCCCC(CCCCCCCCCC)COC(C1CCN(CC1)C)=O)OCCC(CCCCC)CCCCC
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (261 KB) Handling Instructions (2659 KB)
References	[1]. Suzuki Y, et al. Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates. Mol Ther Nucleic Acids. 2022 Dec 13;30:226-240. [Content Brief]

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L2022170488-92-1L 202L-202LiposomeIonizablenanoparticlesInhibitorinhibitorinhibit

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L202

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