2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Laccaridione B

Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively.

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Laccaridione B Chemical Structure

Laccaridione B Chemical Structure

CAS No. : 320369-81-1

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Description

Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively[1].

Molecular Weight

398.45

Formula

C23H26O6
CAS No.
SMILES

CCOC1C2=C(C=C(O1)/C(C)=C/C(C)CC)C=C3C(C(C(C(OC)=C3)=O)=O)=C2O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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Laccaridione B Related Classifications

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Keywords:

Laccaridione B320369-81-1Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesInhibitorinhibitorinhibit

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