2. Anti-infection MAPK/ERK Pathway NF-κB
  3. Antibiotic Bacterial Fungal p38 MAPK NF-κB
  4. Lambertellin

Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.

For research use only. We do not sell to patients.

Lambertellin Chemical Structure

Lambertellin Chemical Structure

CAS No. : 28980-51-0

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Lambertellin Related Antibodies

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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Description

Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways[1].

In Vitro

In lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells, Lambertellin exhibits promising inhibitory activity against nitric oxide (NO) production with an IC50 value of 3.19 µM, and it significantly inhibits the expression of inducible NO synthase (iNOS) and cyclooxygenase 2 (COX-2). Lambertellin also decreases the expression of pro-inflammatory cytokines IL-6 and IL-1β[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lambertellin Related Antibodies
Molecular Weight

256.21

Formula

C14H8O5
CAS No.
SMILES

O=C1OC(C(C2=C3C=CC=C2O)=O)=C(C=C1C)C3=O
Structure Classification
Initial Source

Lambertella sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lambertellin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lambertellin28980-51-0AntibioticBacterialFungalp38 MAPKNF-κBNuclear factor-κBNuclear factor-kappaBIL-6IL-1βNONO synthase (iNOS)COX-2bactericidefungicideantibioticInhibitorinhibitorinhibit

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