Ledaborbactam (Synonyms: VNRX-5236)

Cat. No.: HY-132823 Purity: 99.12%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Iedaborbactam (VNRX-5236), as a β-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections.

For research use only. We do not sell to patients.

Ledaborbactam Chemical Structure

CAS No. : 1842397-36-7

Size		Stock
5 mg		Check price and availability
10 mg		Check price and availability

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

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Metallo-β-lactamase

Biological Activity
Purity & Documentation
References
Customer Review

Description

Iedaborbactam (VNRX-5236), as a β-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections^[1].

IC₅₀ & Target

beta-lactamase^[1]

In Vitro

Iedaborbactam is a beta-lactamase inhibitor^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

263.05

Formula

C₁₂H₁₄BNO₅

CAS No.

1842397-36-7

Appearance

Solid

Color

White to off-white

SMILES

OC(C1=C2C(C[C@@H](B(O2)O)NC(CC)=O)=CC=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (380.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8016 mL	19.0078 mL	38.0156 mL
5 mM	0.7603 mL	3.8016 mL	7.6031 mL
10 mM	0.3802 mL	1.9008 mL	3.8016 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.12%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (250 KB) HNMR (225 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. WO2015191907

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8016 mL	19.0078 mL	38.0156 mL	95.0390 mL
	5 mM	0.7603 mL	3.8016 mL	7.6031 mL	19.0078 mL
	10 mM	0.3802 mL	1.9008 mL	3.8016 mL	9.5039 mL
	15 mM	0.2534 mL	1.2672 mL	2.5344 mL	6.3359 mL
	20 mM	0.1901 mL	0.9504 mL	1.9008 mL	4.7519 mL
	25 mM	0.1521 mL	0.7603 mL	1.5206 mL	3.8016 mL
	30 mM	0.1267 mL	0.6336 mL	1.2672 mL	3.1680 mL
	40 mM	0.0950 mL	0.4752 mL	0.9504 mL	2.3760 mL
	50 mM	0.0760 mL	0.3802 mL	0.7603 mL	1.9008 mL
	60 mM	0.0634 mL	0.3168 mL	0.6336 mL	1.5840 mL
	80 mM	0.0475 mL	0.2376 mL	0.4752 mL	1.1880 mL
	100 mM	0.0380 mL	0.1901 mL	0.3802 mL	0.9504 mL

Ledaborbactam Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ledaborbactam1842397-36-7VNRX-5236VNRX5236VNRX 5236Beta-lactamaseBacterialβ-lactamaselactamasebacterialinfectionsantibioticsbactericidallow-toxicityInhibitorinhibitorinhibit

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