1. Inhibitory Antibodies
  2. Lepunafusp alfa

Lepunafusp alfa  (Synonyms: JR-171)

Cat. No.: HY-P99694

Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I.

For research use only. We do not sell to patients.

CAS No. : 2396411-71-3

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Description

Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I[1][2].

Isotype

F(ab')2-G1-kappa

Species

Humanized

Clinical Trial
CAS No.
SMILES

[Lepunafusp alfa]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • F(ab')2-G1-kappa
Purity & Documentation
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Lepunafusp alfa Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lepunafusp alfa
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