Linoleyl alcohol

Cat. No.: HY-W005627 Purity: 99.84%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Linoleyl alcohol, a structural analog of Linoleic acid with no a-carboxyl group, is a fatty alcohol.

For research use only. We do not sell to patients.

Linoleyl alcohol Chemical Structure

CAS No. : 506-43-4

Size	Price	Stock	Quantity
500 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
1 g	USD 64	In-stock	Estimated Time of Arrival: December 31
5 g		Get quote
10 g		Get quote

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Other Forms of Linoleyl alcohol:

Linoleyl alcohol (Standard) Get quote

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Biological Activity
Purity & Documentation
References
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Description

Linoleyl alcohol, a structural analog of Linoleic acid with no a-carboxyl group, is a fatty alcohol^[1].

In Vitro

The dioxygenation of Linoleyl alcohol by potato tuber lipoxygenase leads to formation of two positional isomeric products-9- and 13-hydroperoxyoctadecadien-1-ols^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Animal feeding experiments have revealed that esters made from Gallic acid (GA) and (-)-Epigallo-catechin (EGC) or Linoleyl alcohol are more effective in weight-loss promotion and metabolic syndrome management than are intact GA and EGC^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

266.46

Formula

C₁₈H₃₄O

CAS No.

506-43-4

Appearance

Liquid (Density: 0.8588 g/cm³)

Color

Colorless to light yellow

SMILES

CCCCC/C=C\C/C=C\CCCCCCCCO

Structure Classification

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (375.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7529 mL	18.7645 mL	37.5291 mL
5 mM	0.7506 mL	3.7529 mL	7.5058 mL
10 mM	0.3753 mL	1.8765 mL	3.7529 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.38 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (9.38 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (9.38 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.84%

Select Batch:

Data Sheet (265 KB) SDS (393 KB)

COA (237 KB) HNMR (236 KB) RP-HPLC (243 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. I A Butovich, et al. Oxidation of linoleyl alcohol by potato tuber lipoxygenase: kinetics and positional, stereo, and geometrical (cis, trans) specificity of the reaction. Arch Biochem Biophys. 2000 Jun 1;378(1):65-77. [Content Brief]

[2]. Nagao Totani, et al. Gallic acid glycerol ester promotes weight-loss in rats. J Oleo Sci. 2011;60(9):457-62. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7529 mL	18.7645 mL	37.5291 mL	93.8227 mL
	5 mM	0.7506 mL	3.7529 mL	7.5058 mL	18.7645 mL
	10 mM	0.3753 mL	1.8765 mL	3.7529 mL	9.3823 mL
	15 mM	0.2502 mL	1.2510 mL	2.5019 mL	6.2548 mL
	20 mM	0.1876 mL	0.9382 mL	1.8765 mL	4.6911 mL
	25 mM	0.1501 mL	0.7506 mL	1.5012 mL	3.7529 mL
	30 mM	0.1251 mL	0.6255 mL	1.2510 mL	3.1274 mL
	40 mM	0.0938 mL	0.4691 mL	0.9382 mL	2.3456 mL
	50 mM	0.0751 mL	0.3753 mL	0.7506 mL	1.8765 mL
	60 mM	0.0625 mL	0.3127 mL	0.6255 mL	1.5637 mL
	80 mM	0.0469 mL	0.2346 mL	0.4691 mL	1.1728 mL
	100 mM	0.0375 mL	0.1876 mL	0.3753 mL	0.9382 mL