2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. Lu AA33810

Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects.

For research use only. We do not sell to patients.

Lu AA33810 Chemical Structure

Lu AA33810 Chemical Structure

CAS No. : 304008-29-5

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Based on 1 publication(s) in Google Scholar

Lu AA33810 Related Antibodies

Top Publications Citing Use of Products

View All Neuropeptide Y Receptor Isoform Specific Products:

View All Isoforms
NPY Y1 receptor NPY Y2 receptor NPY Y4 receptor NPY Y5 receptor

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Description

Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects[1].

IC50 & Target

hY5 receptor

1.5 nM (Ki)

Molecular Weight

423.62

Formula

C19H25N3O2S3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CS(NC[C@@H](CC1)CC[C@H]1NC2=NC3=C(S2)CCSC4=CC=CC=C34)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 42.36 mg/mL (100.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3606 mL 11.8030 mL 23.6061 mL
5 mM 0.4721 mL 2.3606 mL 4.7212 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3606 mL 11.8030 mL 23.6061 mL 59.0152 mL
5 mM 0.4721 mL 2.3606 mL 4.7212 mL 11.8030 mL
10 mM 0.2361 mL 1.1803 mL 2.3606 mL 5.9015 mL
15 mM 0.1574 mL 0.7869 mL 1.5737 mL 3.9343 mL
20 mM 0.1180 mL 0.5902 mL 1.1803 mL 2.9508 mL
25 mM 0.0944 mL 0.4721 mL 0.9442 mL 2.3606 mL
30 mM 0.0787 mL 0.3934 mL 0.7869 mL 1.9672 mL
40 mM 0.0590 mL 0.2951 mL 0.5902 mL 1.4754 mL
50 mM 0.0472 mL 0.2361 mL 0.4721 mL 1.1803 mL
60 mM 0.0393 mL 0.1967 mL 0.3934 mL 0.9836 mL
80 mM 0.0295 mL 0.1475 mL 0.2951 mL 0.7377 mL
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Lu AA33810 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lu AA33810304008-29-5Lu AA 33810Lu AA-33810Neuropeptide Y ReceptorNPY receptorInhibitorinhibitorinhibit

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