Mal-PEG2-oxyamine TFA

Cat. No.: HY-133454A Purity: 96.46%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Mal-PEG2-oxyamine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Mal-PEG2-oxyamine TFA Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of Mal-PEG2-oxyamine TFA:

Mal-PEG2-oxyamine Get quote

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Biological Activity
Purity & Documentation
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Description

Mal-PEG2-oxyamine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

358.27

Formula

C₁₂H₁₇F₃N₂O₇

Appearance

Liquid

Color

Colorless to light yellow

SMILES

NOCCOCCOCCN1C(C=CC1=O)=O.O=C(O)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (697.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7912 mL	13.9560 mL	27.9119 mL
5 mM	0.5582 mL	2.7912 mL	5.5824 mL
10 mM	0.2791 mL	1.3956 mL	2.7912 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.46%

Select Batch:

Data Sheet (243 KB) SDS (251 KB)

COA (247 KB) HNMR (283 KB) RP-HPLC (228 KB) MS (89 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7912 mL	13.9560 mL	27.9119 mL	69.7798 mL
	5 mM	0.5582 mL	2.7912 mL	5.5824 mL	13.9560 mL
	10 mM	0.2791 mL	1.3956 mL	2.7912 mL	6.9780 mL
	15 mM	0.1861 mL	0.9304 mL	1.8608 mL	4.6520 mL
	20 mM	0.1396 mL	0.6978 mL	1.3956 mL	3.4890 mL
	25 mM	0.1116 mL	0.5582 mL	1.1165 mL	2.7912 mL
	30 mM	0.0930 mL	0.4652 mL	0.9304 mL	2.3260 mL
	40 mM	0.0698 mL	0.3489 mL	0.6978 mL	1.7445 mL
	50 mM	0.0558 mL	0.2791 mL	0.5582 mL	1.3956 mL
	60 mM	0.0465 mL	0.2326 mL	0.4652 mL	1.1630 mL
	80 mM	0.0349 mL	0.1744 mL	0.3489 mL	0.8722 mL
	100 mM	0.0279 mL	0.1396 mL	0.2791 mL	0.6978 mL