2. Neuronal Signaling
  3. Monoamine Oxidase
  4. MAO-B-IN-8

MAO-B-IN-8 is a potent reversible MAO-B inhibitor and an inhibitor of microglial production of neuroinflammatory mediator. MAO-B-IN-8 can be used for neurodegenerative disease research.

For research use only. We do not sell to patients.

MAO-B-IN-8 Chemical Structure

MAO-B-IN-8 Chemical Structure

CAS No. : 1638956-60-1

Size Price Stock Quantity
5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg USD 850 In-stock
100 mg USD 1350 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

MAO-B-IN-8 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE MAO-B-IN-8

View All Monoamine Oxidase Isoform Specific Products:

View All Isoforms
MAO-A MAO-B

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MAO-B-IN-8 is a potent reversible MAO-B inhibitor and an inhibitor of microglial production of neuroinflammatory mediator. MAO-B-IN-8 can be used for neurodegenerative disease research[1].

IC50 & Target[1]

MAO-B

 

Molecular Weight

328.32

Formula

C18H16O6
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

COC1=C(C(OC)=C(C=C1)/C=C2OC3=C(C\2=O)C=CC(O)=C3)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (380.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0458 mL 15.2290 mL 30.4581 mL
5 mM 0.6092 mL 3.0458 mL 6.0916 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0458 mL 15.2290 mL 30.4581 mL 76.1452 mL
5 mM 0.6092 mL 3.0458 mL 6.0916 mL 15.2290 mL
10 mM 0.3046 mL 1.5229 mL 3.0458 mL 7.6145 mL
15 mM 0.2031 mL 1.0153 mL 2.0305 mL 5.0763 mL
20 mM 0.1523 mL 0.7615 mL 1.5229 mL 3.8073 mL
25 mM 0.1218 mL 0.6092 mL 1.2183 mL 3.0458 mL
30 mM 0.1015 mL 0.5076 mL 1.0153 mL 2.5382 mL
40 mM 0.0761 mL 0.3807 mL 0.7615 mL 1.9036 mL
50 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.5229 mL
60 mM 0.0508 mL 0.2538 mL 0.5076 mL 1.2691 mL
80 mM 0.0381 mL 0.1904 mL 0.3807 mL 0.9518 mL
100 mM 0.0305 mL 0.1523 mL 0.3046 mL 0.7615 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

MAO-B-IN-8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAO-B-IN-81638956-60-1Monoamine OxidaseMAOneurodegenerative diseaseMAO-B inhibitorNatural products analogueParkinson’s diseaseneuroinflammationInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
MAO-B-IN-8
Cat. No.:
HY-146958
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.