2. Autophagy
  3. Autophagy
  4. Maprotiline-d3 hydrochloride

Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride).

For research use only. We do not sell to patients.

Maprotiline-d<sub>3</sub> hydrochloride Chemical Structure

Maprotiline-d3 hydrochloride Chemical Structure

CAS No. : 1329496-63-0

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1 mg USD 300 In-stock
5 mg USD 900 In-stock
10 mg USD 1550 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Maprotiline-d3 hydrochloride:

Maprotiline-d3 hydrochloride Related Antibodies

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Description

Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride).

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Maprotiline-d3 hydrochloride Related Antibodies
Molecular Weight

316.88

Formula

C20H21D3ClN
CAS No.
Unlabeled CAS

10347-81-6
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])NCCCC12C3=CC=CC=C3C(CC2)C4=CC=CC=C41.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (262.97 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 83.33 mg/mL (262.97 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 2.2 mg/mL (6.94 mM; Need ultrasonic)

H2O : 2.2 mg/mL (6.94 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1558 mL 15.7788 mL 31.5577 mL
5 mM 0.6312 mL 3.1558 mL 6.3115 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO / DMSO 1 mM 3.1558 mL 15.7788 mL 31.5577 mL 78.8942 mL
5 mM 0.6312 mL 3.1558 mL 6.3115 mL 15.7788 mL
DMSO / DMSO 10 mM 0.3156 mL 1.5779 mL 3.1558 mL 7.8894 mL
15 mM 0.2104 mL 1.0519 mL 2.1038 mL 5.2596 mL
20 mM 0.1578 mL 0.7889 mL 1.5779 mL 3.9447 mL
25 mM 0.1262 mL 0.6312 mL 1.2623 mL 3.1558 mL
30 mM 0.1052 mL 0.5260 mL 1.0519 mL 2.6298 mL
40 mM 0.0789 mL 0.3945 mL 0.7889 mL 1.9724 mL
50 mM 0.0631 mL 0.3156 mL 0.6312 mL 1.5779 mL
60 mM 0.0526 mL 0.2630 mL 0.5260 mL 1.3149 mL
80 mM 0.0394 mL 0.1972 mL 0.3945 mL 0.9862 mL
100 mM 0.0316 mL 0.1578 mL 0.3156 mL 0.7889 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Maprotiline-d3 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Maprotiline-d31329496-63-0AutophagyInhibitorinhibitorinhibit

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