2. Cell Cycle/DNA Damage Cytoskeleton
  3. MASTL
  4. MASTL-IN-2

MASTL-IN-2 is an MASTL (microtubule-associated serine/threonine kinase-like) inhibitor. MASTL-IN-2 inhibits human epithelial MIA PaCa cancer cell proliferation with IC50 of 2.8 nM.

For research use only. We do not sell to patients.

MASTL-IN-2 Chemical Structure

MASTL-IN-2 Chemical Structure

CAS No. : 3024916-69-3

Size Price Stock Quantity
1 mg USD 262 In-stock
5 mg USD 656 In-stock
10 mg USD 1050 In-stock
25 mg USD 2100 In-stock
50 mg USD 3365 In-stock
100 mg USD 5385 In-stock
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Based on 1 publication(s) in Google Scholar

MASTL-IN-2 Related Antibodies

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Description

MASTL-IN-2 is an MASTL (microtubule-associated serine/threonine kinase-like) inhibitor. MASTL-IN-2 inhibits human epithelial MIA PaCa cancer cell proliferation with IC50 of 2.8 nM[1].

Molecular Weight

407.47

Formula

C21H25N7O2
CAS No.
Appearance

Crystal

Color

Light yellow to light brown

SMILES

O=C(OCC1)N1C(N=C2N)=CC3=C2C=NC(NC4=NC=CC(C(CC)(N)CC)=C4)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (153.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4542 mL 12.2708 mL 24.5417 mL
5 mM 0.4908 mL 2.4542 mL 4.9083 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4542 mL 12.2708 mL 24.5417 mL 61.3542 mL
5 mM 0.4908 mL 2.4542 mL 4.9083 mL 12.2708 mL
10 mM 0.2454 mL 1.2271 mL 2.4542 mL 6.1354 mL
15 mM 0.1636 mL 0.8181 mL 1.6361 mL 4.0903 mL
20 mM 0.1227 mL 0.6135 mL 1.2271 mL 3.0677 mL
25 mM 0.0982 mL 0.4908 mL 0.9817 mL 2.4542 mL
30 mM 0.0818 mL 0.4090 mL 0.8181 mL 2.0451 mL
40 mM 0.0614 mL 0.3068 mL 0.6135 mL 1.5339 mL
50 mM 0.0491 mL 0.2454 mL 0.4908 mL 1.2271 mL
60 mM 0.0409 mL 0.2045 mL 0.4090 mL 1.0226 mL
80 mM 0.0307 mL 0.1534 mL 0.3068 mL 0.7669 mL
100 mM 0.0245 mL 0.1227 mL 0.2454 mL 0.6135 mL
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MASTL-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MASTL-IN-23024916-69-3MASTLMicrotubule‐associated serine/threonine kinase likeMIA PaCacancerproliferationInhibitorinhibitorinhibit

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