2. Academic Validation
  3. Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae)

Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae)

  • Phytother Res. 2002 Nov;16(7):683-5. doi: 10.1002/ptr.1003.
Jonel P Saludes 1,  Mary J Garson,  Scott G Franzblau,  Alicia M Aguinaldo
Affiliations

Affiliation

  • 1 Research Center for the Natural Sciences, University of Santo Tomas, Espana, Manila 1008, Philippines.
PMID: 12410555 DOI: 10.1002/ptr.1003
Abstract

A crude ethanol extract and hexane fraction from Morinda citrifolia Linn. (Rubiaceae) show antitubercular activity. The major constituents of the hexane fraction are E-phytol, cycloartenol, stigmasterol, beta-sitosterol, campesta-5,7,22-trien-3beta-ol and the ketosteroids stigmasta-4-en-3-one and stigmasta-4-22-dien-3-one. E-Phytol, a mixture of the two ketosteroids, and the epidioxysterol derived from campesta-5,7,22-trien-3beta-ol all show pronounced antitubercular activity.

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