2. Neuronal Signaling
  3. Huntingtin
  4. mHTT-IN-1

mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM.

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mHTT-IN-1 Chemical Structure

mHTT-IN-1 Chemical Structure

CAS No. : 2839311-21-4

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mHTT-IN-1 Related Antibodies

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Description

mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].

Molecular Weight

381.45

Formula

C18H19N7OS
CAS No.
SMILES

O=C1C=C(C2=NN3C=C(C)N=C3C(C)=C2)N=C4SC(N5CCNCC5)=CN14
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Purity & Documentation
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mHTT-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mHTT-IN-12839311-21-4HuntingtinInhibitorinhibitorinhibit

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