2. Epigenetics
  3. MicroRNA
  4. MicroRNA modulator-1

MicroRNA modulator-1 (TABLE4 compound 1) is an oxadiazole miR-21 inhibitor with AC50 of 14.64 μM.

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MicroRNA modulator-1 Chemical Structure

MicroRNA modulator-1 Chemical Structure

CAS No. : 756865-61-9

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10 mg USD 175 In-stock
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MicroRNA modulator-1 Related Antibodies

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Description

MicroRNA modulator-1 (TABLE4 compound 1) is an oxadiazole miR-21 inhibitor with AC50 of 14.64 μM[1].

Molecular Weight

422.54

Formula

C21H30N2O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1CCCCCC1)/C=C/C2=CC=C(C(S(=O)(N3CCOCC3)=O)=C2)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (295.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3666 mL 11.8332 mL 23.6664 mL
5 mM 0.4733 mL 2.3666 mL 4.7333 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3666 mL 11.8332 mL 23.6664 mL 59.1660 mL
5 mM 0.4733 mL 2.3666 mL 4.7333 mL 11.8332 mL
10 mM 0.2367 mL 1.1833 mL 2.3666 mL 5.9166 mL
15 mM 0.1578 mL 0.7889 mL 1.5778 mL 3.9444 mL
20 mM 0.1183 mL 0.5917 mL 1.1833 mL 2.9583 mL
25 mM 0.0947 mL 0.4733 mL 0.9467 mL 2.3666 mL
30 mM 0.0789 mL 0.3944 mL 0.7889 mL 1.9722 mL
40 mM 0.0592 mL 0.2958 mL 0.5917 mL 1.4791 mL
50 mM 0.0473 mL 0.2367 mL 0.4733 mL 1.1833 mL
60 mM 0.0394 mL 0.1972 mL 0.3944 mL 0.9861 mL
80 mM 0.0296 mL 0.1479 mL 0.2958 mL 0.7396 mL
100 mM 0.0237 mL 0.1183 mL 0.2367 mL 0.5917 mL
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MicroRNA modulator-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MicroRNA modulator-1756865-61-9MicroRNA modulator1MicroRNA modulator 1MicroRNAmiRNAInhibitorinhibitorinhibit

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