(-)-Tylophorine (Synonyms: (-)-(R)-Tylophorine; (-)-DCB-3500; (-)-NSC-717335)

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(-)-Tylophorine ((-)-(R)-Tylophorine) is a potent cytotoxic agent with activity against both drug-sensitive and multidrug-resistant cancer cell lines. (-)-Tylophorine has been explored in biomedical research for its anticancer applications.

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(-)-Tylophorine Chemical Structure

CAS No. : 111408-21-0

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Other Forms of (-)-Tylophorine:

Tylophorine Get quote
(+)-(S)-Tylophorine-d8 Get quote

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Description	(-)-Tylophorine ((-)-(R)-Tylophorine) is a potent cytotoxic agent with activity against both drug-sensitive and multidrug-resistant cancer cell lines. (-)-Tylophorine has been explored in biomedical research for its anticancer applications^[1].
Molecular Weight	393.48
Formula	C₂₄H₂₇NO₄
CAS No.	111408-21-0
SMILES	COC1=C(OC)C=C2C3=CC(OC)=C(OC)C=C3C4=C(CN5[C@@](CCC5)([H])C4)C2=C1
Structure Classification	Alkaloids Other Alkaloids
Initial Source	Plants Apocynaceae Tylophora
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Total syntheses of the tylophora alkaloids cryptopleurine, (-)-antofine, (-)-tylophorine, and (-)-ficuseptine C

(-)-Tylophorine Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(-)-Tylophorine111408-21-0(-)-(R)-Tylophorine (-)-DCB-3500 (-)-NSC-717335OthersInhibitorinhibitorinhibit

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(-)-Tylophorine (Synonyms: (-)-(R)-Tylophorine; (-)-DCB-3500; (-)-NSC-717335)

Other Forms of (-)-Tylophorine:

(-)-Tylophorine Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review