Mometasone furoate-d₃  (Synonyms: Sch32088-d₃)

Mometasone furoate-d₃ is a deuterium labeled Mometasone furoate. Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

524.45

C₂₇H₂₇D₃Cl₂O₆

83919-23-7

Solid

White to off-white

C[C@@]12[C@](C(CCl)=O)(OC(C3=C([2H])C([2H])=C([2H])O3)=O)[C@H](C)C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(Cl)[C@@H](O)C2)=O

Room temperature in continental US; may vary elsewhere.

• [1]. Galuppo M, et al. Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids. Pharmacol Res. 2015;99:316-328.  [Content Brief]

  [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]