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  3. Isotope-Labeled Compounds
  4. Mono-(2-ethylhexyl) phthalate-d4

Mono-(2-ethylhexyl) phthalate-d4  (Synonyms: MEHP-d4; Phthalic acid mono-2-ethylhexyl ester-d4)

Cat. No.: HY-W018392S
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Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD).

For research use only. We do not sell to patients.

Mono-(2-ethylhexyl) phthalate-d<sub>4</sub> Chemical Structure

Mono-(2-ethylhexyl) phthalate-d4 Chemical Structure

CAS No. : 1276197-22-8

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Other Forms of Mono-(2-ethylhexyl) phthalate-d4:

Mono-(2-ethylhexyl) phthalate-d4 Related Antibodies

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Description

Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD)[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mono-(2-ethylhexyl) phthalate-d4 Related Antibodies
Molecular Weight

282.37

Formula

C16H18D4O4
CAS No.
Unlabeled CAS

4376-20-9
Appearance

Liquid

Color

Colorless to off-white

SMILES

CCCCC(CC)COC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (354.15 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5415 mL 17.7073 mL 35.4145 mL
5 mM 0.7083 mL 3.5415 mL 7.0829 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5415 mL 17.7073 mL 35.4145 mL 88.5363 mL
5 mM 0.7083 mL 3.5415 mL 7.0829 mL 17.7073 mL
10 mM 0.3541 mL 1.7707 mL 3.5415 mL 8.8536 mL
15 mM 0.2361 mL 1.1805 mL 2.3610 mL 5.9024 mL
20 mM 0.1771 mL 0.8854 mL 1.7707 mL 4.4268 mL
25 mM 0.1417 mL 0.7083 mL 1.4166 mL 3.5415 mL
30 mM 0.1180 mL 0.5902 mL 1.1805 mL 2.9512 mL
40 mM 0.0885 mL 0.4427 mL 0.8854 mL 2.2134 mL
50 mM 0.0708 mL 0.3541 mL 0.7083 mL 1.7707 mL
60 mM 0.0590 mL 0.2951 mL 0.5902 mL 1.4756 mL
80 mM 0.0443 mL 0.2213 mL 0.4427 mL 1.1067 mL
100 mM 0.0354 mL 0.1771 mL 0.3541 mL 0.8854 mL
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Mono-(2-ethylhexyl) phthalate-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mono-(2-ethylhexyl) phthalate-d41276197-22-8MEHP-d4 Phthalic acid mono-2-ethylhexyl ester-d4Isotope-Labeled CompoundsDEHPNAFLDfatty acidhepatocytesInhibitorinhibitorinhibit

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