1. Metabolic Enzyme/Protease GPCR/G Protein
  2. GPR109A Drug Metabolite
  3. Monomethyl fumarate-d3

Monomethyl fumarate-d3 is a deuterium labeled Monomethyl fumarate. Monomethyl fumarate is the primary metabolite of dimethyl fumarate[1].

For research use only. We do not sell to patients.

Monomethyl fumarate-d<sub>3</sub> Chemical Structure

Monomethyl fumarate-d3 Chemical Structure

CAS No. : 1616345-41-5

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1 mg USD 180 In-stock
5 mg USD 520 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Monomethyl fumarate-d3 is a deuterium labeled Monomethyl fumarate. Monomethyl fumarate is the primary metabolite of dimethyl fumarate[1].

Molecular Weight

133.12

Formula

C5H3D3O4

CAS No.
Unlabeled CAS

2756-87-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(OC([2H])([2H])[2H])/C=C/C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (375.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (375.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (75.12 mM; ultrasonic and warming and heat to 60°C)

H2O : 10 mg/mL (75.12 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.5120 mL 37.5601 mL 75.1202 mL
5 mM 1.5024 mL 7.5120 mL 15.0240 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO / DMSO 1 mM 7.5120 mL 37.5601 mL 75.1202 mL 187.8005 mL
5 mM 1.5024 mL 7.5120 mL 15.0240 mL 37.5601 mL
10 mM 0.7512 mL 3.7560 mL 7.5120 mL 18.7800 mL
15 mM 0.5008 mL 2.5040 mL 5.0080 mL 12.5200 mL
20 mM 0.3756 mL 1.8780 mL 3.7560 mL 9.3900 mL
25 mM 0.3005 mL 1.5024 mL 3.0048 mL 7.5120 mL
30 mM 0.2504 mL 1.2520 mL 2.5040 mL 6.2600 mL
40 mM 0.1878 mL 0.9390 mL 1.8780 mL 4.6950 mL
50 mM 0.1502 mL 0.7512 mL 1.5024 mL 3.7560 mL
60 mM 0.1252 mL 0.6260 mL 1.2520 mL 3.1300 mL
DMSO / DMSO 80 mM 0.0939 mL 0.4695 mL 0.9390 mL 2.3475 mL
100 mM 0.0751 mL 0.3756 mL 0.7512 mL 1.8780 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Monomethyl fumarate-d3
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