2. Immunology/Inflammation
  3. CD20 CD3
  4. Mosunetuzumab

Mosunetuzumab  (Synonyms: BTCT-4465A)

Cat. No.: HY-P99033
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Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs).

For research use only. We do not sell to patients.

CAS No. : 1905409-39-3

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5 mg USD 710 In-stock
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Based on 1 publication(s) in Google Scholar

Mosunetuzumab Related Antibodies

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Description

Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs)[1][2].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Bispecific; Humanized

In Vitro

Mosunetuzumab has two arms. One arm binds specifically to CD3 on T-cells and the other to CD20 present on normal and neoplastic B-cells. Simultaneous binding of both arms to their respective targets facilitates T-cell-mediated killing of CD20+ B-cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mosunetuzumab Related Antibodies
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Mosunetuzumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation
References
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Mosunetuzumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mosunetuzumab1905409-39-3BTCT-4465ACD20CD3Cluster of differentiation 3immunoglobulin G1-based bispecific antibodyrelapsed or refractory B-cell non-Hodgkin lymphomasB-NHLsInhibitorinhibitorinhibit

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