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Moxilubant  (Synonyms: CGS 25019C free base)

Cat. No.: HY-106929 Purity: 99.83%
SDS COA Handling Instructions

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Moxilubant (CGS-25019C;LTB-019) is an orally active BLT1 antagonist which inhibits LTB4 signaling with a potency of 2–4 nM. Moxilubant can be used for cancer research.

For research use only. We do not sell to patients.

Moxilubant Chemical Structure

Moxilubant Chemical Structure

CAS No. : 146978-48-5

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5 mg USD 495 In-stock
10 mg USD 735 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Moxilubant:

Moxilubant Related Antibodies

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Description

Moxilubant (CGS-25019C;LTB-019) is an orally active BLT1 antagonist which inhibits LTB4 signaling with a potency of 2–4 nM. Moxilubant can be used for cancer research[1].

Molecular Weight

455.59

Formula

C26H37N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)N(C(C)C)C(C1=CC(OC)=C(OCCCCCOC2=CC=C(C(N)=N)C=C2)C=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (137.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1950 mL 10.9748 mL 21.9496 mL
5 mM 0.4390 mL 2.1950 mL 4.3899 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.83%

SDS (251 KB)

COA (243 KB) HNMR (268 KB) LCMS (91 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1950 mL 10.9748 mL 21.9496 mL 54.8739 mL
5 mM 0.4390 mL 2.1950 mL 4.3899 mL 10.9748 mL
10 mM 0.2195 mL 1.0975 mL 2.1950 mL 5.4874 mL
15 mM 0.1463 mL 0.7317 mL 1.4633 mL 3.6583 mL
20 mM 0.1097 mL 0.5487 mL 1.0975 mL 2.7437 mL
25 mM 0.0878 mL 0.4390 mL 0.8780 mL 2.1950 mL
30 mM 0.0732 mL 0.3658 mL 0.7317 mL 1.8291 mL
40 mM 0.0549 mL 0.2744 mL 0.5487 mL 1.3718 mL
50 mM 0.0439 mL 0.2195 mL 0.4390 mL 1.0975 mL
60 mM 0.0366 mL 0.1829 mL 0.3658 mL 0.9146 mL
80 mM 0.0274 mL 0.1372 mL 0.2744 mL 0.6859 mL
100 mM 0.0219 mL 0.1097 mL 0.2195 mL 0.5487 mL
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Moxilubant Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Moxilubant146978-48-5CGS 25019COthersBLT1LTB4cancerInhibitorinhibitorinhibit

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