2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Muscarine iodide

Muscarine iodide  (Synonyms: (+)-Muscarine iodide)

Cat. No.: HY-107654 Purity: ≥97.0%
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Muscarine ((+)-Muscarine) iodide is a toxin that can stimulate the parasympathetic nervous system. Muscarine iodide is a prototype muscarinic acetylcholine receptor agonist.

For research use only. We do not sell to patients.

Muscarine iodide Chemical Structure

Muscarine iodide Chemical Structure

CAS No. : 24570-49-8

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1 mg USD 190 In-stock
5 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Muscarine iodide:

Muscarine iodide Related Antibodies

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  • Biological Activity

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Description

Muscarine ((+)-Muscarine) iodide is a toxin that can stimulate the parasympathetic nervous system. Muscarine iodide is a prototype muscarinic acetylcholine receptor agonist[1][2].

In Vitro

Muscarine iodide administration (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM ACh[1].
Muscarine iodide (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Muscarine iodide Related Antibodies
Molecular Weight

301.17

Formula

C9H20INO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)C[C@@H]1C[C@@H](O)[C@H](C)O1.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (166.02 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3204 mL 16.6019 mL 33.2038 mL
5 mM 0.6641 mL 3.3204 mL 6.6408 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.3204 mL 16.6019 mL 33.2038 mL 83.0096 mL
5 mM 0.6641 mL 3.3204 mL 6.6408 mL 16.6019 mL
10 mM 0.3320 mL 1.6602 mL 3.3204 mL 8.3010 mL
15 mM 0.2214 mL 1.1068 mL 2.2136 mL 5.5340 mL
20 mM 0.1660 mL 0.8301 mL 1.6602 mL 4.1505 mL
25 mM 0.1328 mL 0.6641 mL 1.3282 mL 3.3204 mL
30 mM 0.1107 mL 0.5534 mL 1.1068 mL 2.7670 mL
40 mM 0.0830 mL 0.4150 mL 0.8301 mL 2.0752 mL
50 mM 0.0664 mL 0.3320 mL 0.6641 mL 1.6602 mL
60 mM 0.0553 mL 0.2767 mL 0.5534 mL 1.3835 mL
80 mM 0.0415 mL 0.2075 mL 0.4150 mL 1.0376 mL
100 mM 0.0332 mL 0.1660 mL 0.3320 mL 0.8301 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Muscarine iodide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Muscarine24570-49-8(+)-MuscarinemAChRMuscarinic acetylcholine receptorintracellular calciumNRMneuronInhibitorinhibitorinhibit

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