2. Apoptosis
  3. Apoptosis Bcl-2 Family
  4. n-Butyl-β-D-fructofuranoside

n-Butyl-β-D-fructofuranoside 

Cat. No.: HY-N9802 Purity: ≥97.0%
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n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research.

For research use only. We do not sell to patients.

n-Butyl-β-D-fructofuranoside Chemical Structure

n-Butyl-β-D-fructofuranoside Chemical Structure

CAS No. : 80971-60-4

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Based on 1 publication(s) in Google Scholar

n-Butyl-β-D-fructofuranoside Related Antibodies

Top Publications Citing Use of Products

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim

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Description

n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research[1].

IC50 & Target[1]

Bax

 

Bcl-2

 

In Vitro

n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells[1].
n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

n-Butyl-β-D-fructofuranoside Related Antibodies

Cell Viability Assay[1]

Cell Line: Bel-7402 cells
Concentration: 0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL
Incubation Time: 24, 48 and 72 hours
Result: Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner.

Cell Cycle Analysis[1]

Cell Line: Bel-7402 cells
Concentration: 0, 50 and 75 μg/mL
Incubation Time: 24, 48 and 72 hours
Result: Induced cell cycle arrest at G0/G1 phase.

Western Blot Analysis[1]

Cell Line: Bel-7402 cells
Concentration: 23.6 μg/mL
Incubation Time: 0, 24, 48 and 72 hours
Result: Decreased Bcl-2 and increased Bax and p53 levels in a time manner.
Molecular Weight

236.26

Formula

C10H20O6
CAS No.
Appearance

Oil

Color

Light yellow to yellow

SMILES

CCCCO[C@](O[C@@H]1CO)([C@H]([C@@H]1O)O)CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (423.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2326 mL 21.1631 mL 42.3263 mL
5 mM 0.8465 mL 4.2326 mL 8.4653 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

COA (246 KB) HNMR (236 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2326 mL 21.1631 mL 42.3263 mL 105.8156 mL
5 mM 0.8465 mL 4.2326 mL 8.4653 mL 21.1631 mL
10 mM 0.4233 mL 2.1163 mL 4.2326 mL 10.5816 mL
15 mM 0.2822 mL 1.4109 mL 2.8218 mL 7.0544 mL
20 mM 0.2116 mL 1.0582 mL 2.1163 mL 5.2908 mL
25 mM 0.1693 mL 0.8465 mL 1.6931 mL 4.2326 mL
30 mM 0.1411 mL 0.7054 mL 1.4109 mL 3.5272 mL
40 mM 0.1058 mL 0.5291 mL 1.0582 mL 2.6454 mL
50 mM 0.0847 mL 0.4233 mL 0.8465 mL 2.1163 mL
60 mM 0.0705 mL 0.3527 mL 0.7054 mL 1.7636 mL
80 mM 0.0529 mL 0.2645 mL 0.5291 mL 1.3227 mL
100 mM 0.0423 mL 0.2116 mL 0.4233 mL 1.0582 mL
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n-Butyl-β-D-fructofuranoside Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

n-Butyl-β-D-fructofuranoside80971-60-4ApoptosisBcl-2 Familymitochondrial pathwaykangaisannature productcancerInhibitorinhibitorinhibit

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