1. Others
  2. Isotope-Labeled Compounds
  3. N-Nitrosomorpholine-d8

N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].

For research use only. We do not sell to patients.

N-Nitrosomorpholine-d<sub>8</sub> Chemical Structure

N-Nitrosomorpholine-d8 Chemical Structure

CAS No. : 1219805-76-1

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10 mg USD 360 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

124.17

Formula

C4D8N2O2

CAS No.
Unlabeled CAS

59-89-2

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=NN1C([2H])([2H])C([2H])([2H])OC([2H])([2H])C1([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (805.35 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.0535 mL 40.2674 mL 80.5348 mL
5 mM 1.6107 mL 8.0535 mL 16.1070 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.0535 mL 40.2674 mL 80.5348 mL 201.3369 mL
5 mM 1.6107 mL 8.0535 mL 16.1070 mL 40.2674 mL
10 mM 0.8053 mL 4.0267 mL 8.0535 mL 20.1337 mL
15 mM 0.5369 mL 2.6845 mL 5.3690 mL 13.4225 mL
20 mM 0.4027 mL 2.0134 mL 4.0267 mL 10.0668 mL
25 mM 0.3221 mL 1.6107 mL 3.2214 mL 8.0535 mL
30 mM 0.2684 mL 1.3422 mL 2.6845 mL 6.7112 mL
40 mM 0.2013 mL 1.0067 mL 2.0134 mL 5.0334 mL
50 mM 0.1611 mL 0.8053 mL 1.6107 mL 4.0267 mL
60 mM 0.1342 mL 0.6711 mL 1.3422 mL 3.3556 mL
80 mM 0.1007 mL 0.5033 mL 1.0067 mL 2.5167 mL
100 mM 0.0805 mL 0.4027 mL 0.8053 mL 2.0134 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N-Nitrosomorpholine-d8
Cat. No.:
HY-131123S1
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