2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
  4. N1-Methylpseudouridine-5′-triphosphate trisodium

N1-Methylpseudouridine-5′-triphosphate trisodium  (Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium)

Cat. No.: HY-112582C Purity: ≥99.0%
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N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

For research use only. We do not sell to patients.

N1-Methylpseudouridine-5′-triphosphate trisodium Chemical Structure

N1-Methylpseudouridine-5′-triphosphate trisodium Chemical Structure

Size Price Stock Quantity
Solvent
5641 μg (100 mM*100 μL in water) USD 150 In-stock
Solvent
11282 μg (100 mM*200 μL in water) USD 240 In-stock
Solvent
28205 μg (100 mM*500 μL in water) USD 470 In-stock
Solvent
56411 μg (100 mM*1 mL in water) USD 750 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of N1-Methylpseudouridine-5′-triphosphate trisodium:

N1-Methylpseudouridine-5′-triphosphate trisodium Related Antibodies

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Description

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability[1].

Molecular Weight

564.11

Formula

C10H14N2Na3O15P3
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
Shipping

Shipping with dry ice.
Storage

-80°C
Solvent & Solubility
In Vitro: 

H2O : ≥ 125 mg/mL (221.59 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7727 mL 8.8635 mL 17.7270 mL
5 mM 0.3545 mL 1.7727 mL 3.5454 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

SDS (251 KB)

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7727 mL 8.8635 mL 17.7270 mL 44.3176 mL
5 mM 0.3545 mL 1.7727 mL 3.5454 mL 8.8635 mL
10 mM 0.1773 mL 0.8864 mL 1.7727 mL 4.4318 mL
15 mM 0.1182 mL 0.5909 mL 1.1818 mL 2.9545 mL
20 mM 0.0886 mL 0.4432 mL 0.8864 mL 2.2159 mL
25 mM 0.0709 mL 0.3545 mL 0.7091 mL 1.7727 mL
30 mM 0.0591 mL 0.2955 mL 0.5909 mL 1.4773 mL
40 mM 0.0443 mL 0.2216 mL 0.4432 mL 1.1079 mL
50 mM 0.0355 mL 0.1773 mL 0.3545 mL 0.8864 mL
60 mM 0.0295 mL 0.1477 mL 0.2955 mL 0.7386 mL
80 mM 0.0222 mL 0.1108 mL 0.2216 mL 0.5540 mL
100 mM 0.0177 mL 0.0886 mL 0.1773 mL 0.4432 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N1-Methylpseudouridine-5′-triphosphate trisodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N1-Methylpseudouridine-5′-triphosphate trisodium1-Methylpseudouridine-5′-triphosphate trisodiumNucleoside Antimetabolite/AnalogDNA/RNA Synthesisnucleobase-modified nucleotidemRNAInhibitorinhibitorinhibit

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