Naratriptan hydrochloride (Standard) (Synonyms: GR-85548A hydrochloride (Standard))

Cat. No.: HY-B0197AR Purity: ≥98%: Handling Instructions Technical Support

Naratriptan (GR-85548A) hydrochloride (Standard) is the analytical standard of Naratriptan hydrochloride (HY-B0197A). This product is intended for research and analytical applications. Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC₅₀=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.

For research use only. We do not sell to patients.

Naratriptan hydrochloride (Standard) Chemical Structure

CAS No. : 143388-64-1

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Description	Naratriptan (GR-85548A) hydrochloride (Standard) is the analytical standard of Naratriptan hydrochloride (HY-B0197A). This product is intended for research and analytical applications. Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC₅₀=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.
Molecular Weight	371.93
Formula	C₁₇H₂₆ClN₃O₂S
CAS No.	143388-64-1
SMILES	O=S(CCC1=CC2=C(NC=C2C3CCN(C)CC3)C=C1)(NC)=O.Cl
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Naratriptan hydrochloride (Standard) Related Classifications

Neurological Disease Inflammation/Immunology Cardiovascular Disease

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	×		=		×
C1		V1		C2		V2

Keywords:

Naratriptan hydrochloride (Standard)143388-64-1GR-85548A hydrochloride (Standard)5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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Naratriptan hydrochloride (Standard) (Synonyms: GR-85548A hydrochloride (Standard))

Product Information

Purity & Documentation

Customer Review

Naratriptan hydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator