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NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells.

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NCGC00262650 Chemical Structure

NCGC00262650 Chemical Structure

CAS No. : 344359-25-7

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5 mg USD 90 In-stock
10 mg USD 140 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells[1].

Molecular Weight

308.38

Formula

C18H20N4O
CAS No.
Appearance

Liquid (Density: 1.33±0.1 g/cm3)

Color

Colorless to light yellow

SMILES

NC1=C2C(N(C3CCCC3)C=C2C4=CC=C(OC)C=C4)=NC=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (405.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2428 mL 16.2138 mL 32.4275 mL
5 mM 0.6486 mL 3.2428 mL 6.4855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2428 mL 16.2138 mL 32.4275 mL 81.0688 mL
5 mM 0.6486 mL 3.2428 mL 6.4855 mL 16.2138 mL
10 mM 0.3243 mL 1.6214 mL 3.2428 mL 8.1069 mL
15 mM 0.2162 mL 1.0809 mL 2.1618 mL 5.4046 mL
20 mM 0.1621 mL 0.8107 mL 1.6214 mL 4.0534 mL
25 mM 0.1297 mL 0.6486 mL 1.2971 mL 3.2428 mL
30 mM 0.1081 mL 0.5405 mL 1.0809 mL 2.7023 mL
40 mM 0.0811 mL 0.4053 mL 0.8107 mL 2.0267 mL
50 mM 0.0649 mL 0.3243 mL 0.6486 mL 1.6214 mL
60 mM 0.0540 mL 0.2702 mL 0.5405 mL 1.3511 mL
80 mM 0.0405 mL 0.2027 mL 0.4053 mL 1.0134 mL
100 mM 0.0324 mL 0.1621 mL 0.3243 mL 0.8107 mL
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NCGC00262650 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NCGC00262650344359-25-7NCGC 00262650NCGC-00262650Othersapical membrane antigen 1rhoptry neck protein 2AMA1-RON2merozoitesInhibitorinhibitorinhibit

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