2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. NCS-382 sodium

NCS-382 (sodium) is a potent GABA receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases.

For research use only. We do not sell to patients.

NCS-382 sodium Chemical Structure

NCS-382 sodium Chemical Structure

CAS No. : 131733-92-1

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Based on 1 publication(s) in Google Scholar

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NCS-382 sodium Related Antibodies

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Description

NCS-382 (sodium) is a potent GABA receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases[1].

Molecular Weight

240.23

Formula

C13H13NaO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])/C=C1CCCC2=CC=CC=C2C\1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 12 mg/mL (49.95 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1627 mL 20.8134 mL 41.6268 mL
5 mM 0.8325 mL 4.1627 mL 8.3254 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

SDS (252 KB)

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1627 mL 20.8134 mL 41.6268 mL 104.0669 mL
5 mM 0.8325 mL 4.1627 mL 8.3254 mL 20.8134 mL
10 mM 0.4163 mL 2.0813 mL 4.1627 mL 10.4067 mL
15 mM 0.2775 mL 1.3876 mL 2.7751 mL 6.9378 mL
20 mM 0.2081 mL 1.0407 mL 2.0813 mL 5.2033 mL
25 mM 0.1665 mL 0.8325 mL 1.6651 mL 4.1627 mL
30 mM 0.1388 mL 0.6938 mL 1.3876 mL 3.4689 mL
40 mM 0.1041 mL 0.5203 mL 1.0407 mL 2.6017 mL
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NCS-382 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NCS-382131733-92-1NCS382NCS 382GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorGABA receptor antagonistInhibitorinhibitorinhibit

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