Neotuberostemonine

Cat. No.: HY-N3196 Purity: 99.56%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages.

For research use only. We do not sell to patients.

Neotuberostemonine Chemical Structure

CAS No. : 143120-46-1

Size	Price	Stock	Quantity
1 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 270	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

375.50

Formula

C₂₂H₃₃NO₄

CAS No.

143120-46-1

Appearance

Solid

Color

White to off-white

SMILES

CC[C@@H]1[C@]2([H])[C@]3([H])[C@](C[C@]([C@](O4)([H])C[C@H](C)C4=O)([H])N3CCCC2)([H])[C@@]([C@@H]5C)([H])[C@]1([H])OC5=O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (133.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6631 mL	13.3156 mL	26.6312 mL
5 mM	0.5326 mL	2.6631 mL	5.3262 mL
10 mM	0.2663 mL	1.3316 mL	2.6631 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.56%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (253 KB) RP-HPLC (126 KB)

Handling Instructions (2659 KB)

References

[1]. Xiang J, et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages. Int Immunopharmacol. 2016 Jul;36:158-164. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6631 mL	13.3156 mL	26.6312 mL	66.5779 mL
	5 mM	0.5326 mL	2.6631 mL	5.3262 mL	13.3156 mL
	10 mM	0.2663 mL	1.3316 mL	2.6631 mL	6.6578 mL
	15 mM	0.1775 mL	0.8877 mL	1.7754 mL	4.4385 mL
	20 mM	0.1332 mL	0.6658 mL	1.3316 mL	3.3289 mL
	25 mM	0.1065 mL	0.5326 mL	1.0652 mL	2.6631 mL
	30 mM	0.0888 mL	0.4439 mL	0.8877 mL	2.2193 mL
	40 mM	0.0666 mL	0.3329 mL	0.6658 mL	1.6644 mL
	50 mM	0.0533 mL	0.2663 mL	0.5326 mL	1.3316 mL
	60 mM	0.0444 mL	0.2219 mL	0.4439 mL	1.1096 mL
	80 mM	0.0333 mL	0.1664 mL	0.3329 mL	0.8322 mL
	100 mM	0.0266 mL	0.1332 mL	0.2663 mL	0.6658 mL