2. Metabolic Enzyme/Protease
  3. Elastase
  4. Neutrophil elastase inhibitor 5

Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (PR3) with IC50 values of 4.91 μM and 20.69 μM, respectively. Neutrophil elastase inhibitor 5 can be used in the study of neutrophil inflammatory diseases.

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Neutrophil elastase inhibitor 5 Chemical Structure

Neutrophil elastase inhibitor 5 Chemical Structure

CAS No. : 3020696-44-7

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Description

Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (PR3) with IC50 values of 4.91 μM and 20.69 μM, respectively. Neutrophil elastase inhibitor 5 can be used in the study of neutrophil inflammatory diseases[1].

IC50 & Target

IC50: 4.91 μM (HNE); 20.69 μM (PR3)[1].
Molecular Weight

426.42

Formula

C24H18N4O4
CAS No.
SMILES

OC([C@H](C1=CC=CC=C1)NC(C2=NC=CC=C2/N=N/C3=C(C=CC=C4)C4=CC=C3O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Neutrophil elastase inhibitor 5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neutrophil elastase inhibitor 53020696-44-7Neutrophil elastase inhibitor5Neutrophil elastase inhibitor-5ElastaseneutrophilinflammatoryInhibitorinhibitorinhibit

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