2. Others Anti-infection
  3. Isotope-Labeled Compounds HIV Reverse Transcriptase
  4. Nevirapine-d4

Nevirapine-d4 is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].

For research use only. We do not sell to patients.

Nevirapine-d<sub>4</sub> Chemical Structure

Nevirapine-d4 Chemical Structure

CAS No. : 1051418-95-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Nevirapine-d4:

Nevirapine-d4 Related Antibodies

Top Publications Citing Use of Products

View All HIV Isoform Specific Products:

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HIV HIV-1 HIV-2

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  • Purity & Documentation

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Description

Nevirapine-d4 is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].

IC50 & Target

HIV-1

 

Molecular Weight

270.32

Formula

C15H10D4N4O
CAS No.
Unlabeled CAS

129618-40-2
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=CC=CN=C2N(C3C([2H])([2H])C3([2H])[2H])C4=NC=CC(C)=C4N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 2.5 mg/mL (9.25 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6993 mL 18.4966 mL 36.9932 mL
5 mM 0.7399 mL 3.6993 mL 7.3986 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6993 mL 18.4966 mL 36.9932 mL 92.4830 mL
5 mM 0.7399 mL 3.6993 mL 7.3986 mL 18.4966 mL
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Nevirapine-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nevirapine-d41051418-95-1Isotope-Labeled CompoundsHIVReverse TranscriptaseHuman immunodeficiency virusdeuteriumAIDSInhibitorinhibitorinhibit

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