2. Anti-infection Cell Cycle/DNA Damage
  3. Parasite Topoisomerase
  4. Niranthin

Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research.

For research use only. We do not sell to patients.

Niranthin Chemical Structure

Niranthin Chemical Structure

CAS No. : 50656-77-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Niranthin:

Niranthin Related Antibodies

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Topoisomerase Topo I Topo II

  • Biological Activity

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  • References

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Description

Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research.

IC50 & Target[2]

Leishmania

 

Topoisomerase

 

Molecular Weight

432.51

Formula

C24H32O7
CAS No.
SMILES

COC1=C2C(OCO2)=CC(C[C@H](COC)[C@@H](COC)CC3=CC(OC)=C(C=C3)OC)=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Niranthin Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Niranthin50656-77-4ParasiteTopoisomerasetopoisomeraseleishmaniasisdrug-resistantanti-leishmanial agentInhibitorinhibitorinhibit

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