2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Nordoxepin hydrochloride

Nordoxepin hydrochloride  (Synonyms: Desmethyldoxepin hydrochloride)

Cat. No.: HY-100046 Purity: 99.94%
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Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the research of mild depression.

For research use only. We do not sell to patients.

Nordoxepin hydrochloride Chemical Structure

Nordoxepin hydrochloride Chemical Structure

CAS No. : 2887-91-4

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1 mg USD 74 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Nordoxepin hydrochloride:

Nordoxepin hydrochloride Related Antibodies

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Description

Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the research of mild depression[1].

Molecular Weight

301.81

Formula

C18H20ClNO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CNCC/C=C1C2=CC=CC=C2OCC3=CC=CC=C/13.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (414.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3133 mL 16.5667 mL 33.1334 mL
5 mM 0.6627 mL 3.3133 mL 6.6267 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3133 mL 16.5667 mL 33.1334 mL 82.8336 mL
5 mM 0.6627 mL 3.3133 mL 6.6267 mL 16.5667 mL
10 mM 0.3313 mL 1.6567 mL 3.3133 mL 8.2834 mL
15 mM 0.2209 mL 1.1044 mL 2.2089 mL 5.5222 mL
20 mM 0.1657 mL 0.8283 mL 1.6567 mL 4.1417 mL
25 mM 0.1325 mL 0.6627 mL 1.3253 mL 3.3133 mL
30 mM 0.1104 mL 0.5522 mL 1.1044 mL 2.7611 mL
40 mM 0.0828 mL 0.4142 mL 0.8283 mL 2.0708 mL
50 mM 0.0663 mL 0.3313 mL 0.6627 mL 1.6567 mL
60 mM 0.0552 mL 0.2761 mL 0.5522 mL 1.3806 mL
80 mM 0.0414 mL 0.2071 mL 0.4142 mL 1.0354 mL
100 mM 0.0331 mL 0.1657 mL 0.3313 mL 0.8283 mL
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Nordoxepin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nordoxepin2887-91-4DesmethyldoxepinDrug MetaboliteDoxepinmetabolitetricyclic antidepressantmild depressionInhibitorinhibitorinhibit

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