2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Nordoxepin hydrochloride

Nordoxepin hydrochloride  (Synonyms: Desmethyldoxepin hydrochloride)

Cat. No.: HY-100046
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Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the research of mild depression.

For research use only. We do not sell to patients.

Nordoxepin hydrochloride Chemical Structure

Nordoxepin hydrochloride Chemical Structure

CAS No. : 2887-91-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Nordoxepin hydrochloride:

Nordoxepin hydrochloride Related Antibodies

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Description

Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the research of mild depression[1].

Molecular Weight

301.81

Formula

C18H20ClNO
CAS No.
SMILES

CNCC/C=C1C2=CC=CC=C2OCC3=CC=CC=C/13.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (99.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3133 mL 16.5667 mL 33.1334 mL
5 mM 0.6627 mL 3.3133 mL 6.6267 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3133 mL 16.5667 mL 33.1334 mL 82.8336 mL
5 mM 0.6627 mL 3.3133 mL 6.6267 mL 16.5667 mL
10 mM 0.3313 mL 1.6567 mL 3.3133 mL 8.2834 mL
15 mM 0.2209 mL 1.1044 mL 2.2089 mL 5.5222 mL
20 mM 0.1657 mL 0.8283 mL 1.6567 mL 4.1417 mL
25 mM 0.1325 mL 0.6627 mL 1.3253 mL 3.3133 mL
30 mM 0.1104 mL 0.5522 mL 1.1044 mL 2.7611 mL
40 mM 0.0828 mL 0.4142 mL 0.8283 mL 2.0708 mL
50 mM 0.0663 mL 0.3313 mL 0.6627 mL 1.6567 mL
60 mM 0.0552 mL 0.2761 mL 0.5522 mL 1.3806 mL
80 mM 0.0414 mL 0.2071 mL 0.4142 mL 1.0354 mL
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Nordoxepin hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nordoxepin2887-91-4DesmethyldoxepinDrug MetaboliteDoxepinmetabolitetricyclic antidepressantmild depressionInhibitorinhibitorinhibit

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