1. Vitamin D Related/Nuclear Receptor
  2. Progesterone Receptor
  3. Norethisterone enanthate

Norethisterone enanthate  (Synonyms: Norigest)

Cat. No.: HY-A0285 Purity: 99.39%
COA Handling Instructions

Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active. Norethisterone enanthate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Norethisterone enanthate Chemical Structure

Norethisterone enanthate Chemical Structure

CAS No. : 3836-23-5

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10 mM * 1 mL in DMSO
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active[1][2][3]. Norethisterone enanthate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

In Vitro

Norethisterone enanthate can be used as an intramuscular contraceptive agent[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Norethisterone enanthate (20-60 mg; p.o.;5 days) inhibits fertility in female rats[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female adult albino rats (Wistar/NIN) weighing around 160-180 g[1]
Dosage: 20, 30, 40, 50, 60 mg
Administration: P.o.; 5 days
Result: A significant reduction in fertility was seen with doses 30 to 60 mg in rats.
Clinical Trial
Molecular Weight

410.59

Formula

C27H38O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C#C[C@]1(OC(CCCCCC)=O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4([H])[C@@]3([H])CC[C@]12C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (487.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4355 mL 12.1776 mL 24.3552 mL
5 mM 0.4871 mL 2.4355 mL 4.8710 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.39%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4355 mL 12.1776 mL 24.3552 mL 60.8880 mL
5 mM 0.4871 mL 2.4355 mL 4.8710 mL 12.1776 mL
10 mM 0.2436 mL 1.2178 mL 2.4355 mL 6.0888 mL
15 mM 0.1624 mL 0.8118 mL 1.6237 mL 4.0592 mL
20 mM 0.1218 mL 0.6089 mL 1.2178 mL 3.0444 mL
25 mM 0.0974 mL 0.4871 mL 0.9742 mL 2.4355 mL
30 mM 0.0812 mL 0.4059 mL 0.8118 mL 2.0296 mL
40 mM 0.0609 mL 0.3044 mL 0.6089 mL 1.5222 mL
50 mM 0.0487 mL 0.2436 mL 0.4871 mL 1.2178 mL
60 mM 0.0406 mL 0.2030 mL 0.4059 mL 1.0148 mL
80 mM 0.0304 mL 0.1522 mL 0.3044 mL 0.7611 mL
100 mM 0.0244 mL 0.1218 mL 0.2436 mL 0.6089 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Norethisterone enanthate
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