Norfenefrine

Cat. No.: HY-B1711: FAQs
Data Sheet Handling Instructions Technical Support

Norfenefrine is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Norfenefrine hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Norfenefrine Chemical Structure

CAS No. : 536-21-0

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This product is a controlled substance and not for sale in your territory.

Other Forms of Norfenefrine:

Norfenefrine hydrochloride Get quote

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α adrenergic receptor β adrenergic receptor

Biological Activity
Purity & Documentation
References
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Description

Norfenefrine is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence^[1]^[2].

IC₅₀ & Target

Adrenergic Receptor^[2]

In Vivo

Norfenefrine (1.25-5.00 mg/kg; s.c.; once) stimulates respiratory tract mucus secretion in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male NMRI mice^[1]
Dosage:	1.25, 2.50, and 5.00 mg/kg
Administration:	Subcutaneous injection, once
Result:	Stimulated intratracheal phenol red secretion.

Molecular Weight

153.18

Formula

C₈H₁₁NO₂

CAS No.

536-21-0

SMILES

OC(CN)C1=CC=CC(O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Engler H, et al. Tracheal phenol red secretion, a new method for screening mucosecretolytic compounds. J Pharmacol Methods. 1984 Jun;11(3):151-7. [Content Brief]

[2]. Jørgensen L, et al. Acute effect of norfenefrine on the urethral pressure profile in females with genuine stress incontinence. Urol Int. 1991;46(2):176-9. [Content Brief]

Norfenefrine Related Classifications

Endocrinology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norfenefrine536-21-0Adrenergic ReceptorBeta Receptorfemale stress incontinenceorally activeendogenously foundInhibitorinhibitorinhibit

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